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KMID : 1161420200230030224
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Journal of Medicinal Food
2020 Volume.23 No. 3 p.224 ~ p.232
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Assessing the Metabolic Impact of Ground Chia Seed in Overweight and Obese Prepubescent Children: Results of a Double-Blind Randomized Clinical Trial
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da Silva Camila Saran
de Arruda Monteiro Camila Ribeiro
da Silva Guilherme Henrique Fagundes
Sarni Roseli Oselka Sacardo
Souza Fabiola Isabel Suano
Feder David
Messias Marcia Cristina Fernandes
de Oliveira Carvalho Patricia
Alberici Rosana M.
Cunha Ildenize B. S.
Eberlin Marcos N.
Rosa Paulo Cesar Pires
Fonseca Fernando Luiz Affonso
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Abstract
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Childhood obesity is a medical condition of major public health concern. Chia seeds are used to treat certain noncommunicable diseases, and they are rich in omega-3 fatty acids, which contribute to the absorption of vitamins. A randomized double-blind clinical trial of 30 obese children was performed. The sample was composed of prepubertal 5- to 10-year-old children of both sexes with body mass indexes equal to or above the 95th percentile who were recruited through the Pediatric Department of the Faculdade de Medicina do ABC. Blood samples were drawn, the children were weighed and measured, and a 24-h dietary recall was obtained before and after the treatment. Not only were significant differences observed for fibrinogen (P?=?.011) but a correlation between the changes in markers and the presence of fibers was also observed for two inflammatory parameters: tumor necrosis factor-α (P?=?.027) and nuclear factor-κβ (P?=?.059). These results indicate that chia seeds may have anti-inflammatory effects related to their fiber content in the context of childhood obesity.
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KEYWORD
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chia seeds (Salvia hispanica L.), childhood obesity, fibers, vitamin E
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